Gene- Vitamin D Interaction and Multiple Sclerosis

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vitamin d and multiple sclerosis.

multiple sclerosis (ms) is a chronic demyelinating disease and also is one of the most common disabling neurological disorders in young and middle-aged adults. the main pathogenesis of ms has long been thought to be an immune mediated disorder of the central nervous system. the function of the immune system is under the influence of vitamin d which as a modulator of immune response could play a...

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Vitamin D and multiple sclerosis

Multiple sclerosis (MS) is a chronic demyelinating disease and also is one of the most common disabling neurological disorders in young and middle-aged adults. The main pathogenesis of MS has long been thought to be an immune mediated disorder of the central nervous system. The function of the immune system is under the influence of vitamin D which as a modulator of immune response could play a...

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Vitamin D and multiple sclerosis.

The hypothesis that adequate vitamin D nutrition can contribute to the prevention of multiple sclerosis (MS) was originally proposed to explain the geographical distribution of MS, but only recently has the relation between various measures of vitamin D (eg, sun exposure, dietary sources, and serum concentrations of 25-hydroxyvitamin D) and risk of developing MS been rigorously investigated. Ov...

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Multiple sclerosis and vitamin D

Andrew J. Solomon, MD WHAT IS VITAMIN D AND WHY IS IT IMPORTANT IN MS? Vitamin D is a vitamin that acts like a hormone in the human body. We get vitamin D from sunlight, food, or dietary supplements. The study by Stein et al.1 examines the relationship of vitamin D and MS. In addition, a recent Patient Page in Neurology focused on the actions of vitamin D and vitamin D deficiency.2 The best lev...

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The Association of Vitamin D Receptor Gene BsmI Polymorphism with Multiple Sclerosis in Iranian Patients

Background & Aims: 1,25-dihydroxyvitamin D3 (1,25 (OH)2 D3), the biologically active form of vitamin D, exerts an immunosuppressive effect through binding to its specific nuclear receptor. The present case-control study was done to examine the possible association of BsmI polymorphism in vitamin D receptor gene (VDR gene) with severity of multiple sclerosis (MS). Methods: 267 Iranian patients w...

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ژورنال

عنوان ژورنال: Pediatric Neurology Briefs

سال: 2010

ISSN: 2166-6482,1043-3155

DOI: 10.15844/pedneurbriefs-24-7-2